Natural Cytotoxicity Receptors: Pattern Recognition and Involvement of Carbohydrates
Natural cytotoxicity receptors (NCRs), expressed by natural killer (NK) cells, trigger NK lysis of tumor and virus-infected cells on interaction with cell-surface ligands of these target cells.We have determined that viral Accessories hemagglutinins expressed on the surface of virus-infected cells are involved in the recognition by the NCRs, NKp44